# A tibble: 4 x 7 # Groups: cluster [4] p_val avg_logFC pct.1 pct.2 p_val_adj cluster gene 1 3.84e-36 0.570 1 0.956 4.16e-32 0 COX6C 2 6.26e- 8 0.292 0.844 0.73 6.80e- 4 2 PGGHG 3 2.22e-29 0.858 0.713 0.259 2.41e-25 3 COL1A1 4 4.61e- 8 0.258 0.356 0.142 5.01e- 4 4 ANKRD30A $`0` GO_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION 7.861638e-07 GO_RESPONSE_TO_TYPE_I_INTERFERON 1.822003e-06 GO_REGULATION_OF_VIRAL_GENOME_REPLICATION 3.174459e-06 GO_NEGATIVE_REGULATION_OF_VIRAL_PROCESS 3.681539e-06 GO_POSITIVE_REGULATION_OF_OSTEOBLAST_PROLIFERATION 3.816330e-06 GO_NEGATIVE_REGULATION_OF_ATPASE_ACTIVITY 5.341549e-06 GO_MAINTENANCE_OF_GASTROINTESTINAL_EPITHELIUM 5.341549e-06 GO_DEFENSE_RESPONSE_TO_BACTERIUM 5.518773e-06 GO_REGULATION_OF_BONE_DEVELOPMENT 7.120315e-06 GO_INNATE_IMMUNE_RESPONSE 7.277520e-06 $`1` GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION 0 GO_CARDIAC_CHAMBER_DEVELOPMENT 0 GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY 0 GO_CIRCADIAN_RHYTHM 0 GO_PHOSPHATIDYLSERINE_ACYL_CHAIN_REMODELING 0 GO_SPINAL_CORD_DEVELOPMENT 0 GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY 0 GO_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS 0 GO_REGULATION_OF_NLRP3_INFLAMMASOME_COMPLEX_ASSEMBLY 0 GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION 0 $`2` GO_NEGATIVE_T_CELL_SELECTION 5.093445e-08 GO_THYMIC_T_CELL_SELECTION 4.753882e-07 GO_POSITIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE 4.753882e-07 GO_REGULATION_OF_MACROPHAGE_CYTOKINE_PRODUCTION 4.753882e-07 GO_POSITIVE_T_CELL_SELECTION 6.112134e-07 GO_PROSTANOID_BIOSYNTHETIC_PROCESS 6.112134e-07 GO_POSITIVE_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION 7.640168e-07 GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE 7.640168e-07 GO_NEGATIVE_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS 7.640168e-07 GO_NEGATIVE_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR 7.640168e-07 $`3` GO_EXTRACELLULAR_MATRIX 6.832940e-22 GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION 1.217530e-19 GO_PROTEINACEOUS_EXTRACELLULAR_MATRIX 2.926139e-18 GO_EXTRACELLULAR_MATRIX_COMPONENT 1.535590e-16 GO_EXTRACELLULAR_SPACE 1.128264e-15 GO_PLATELET_DERIVED_GROWTH_FACTOR_BINDING 6.010622e-13 GO_GROWTH_FACTOR_BINDING 7.237273e-12 GO_MULTICELLULAR_ORGANISMAL_MACROMOLECULE_METABOLIC_PROCESS 9.679133e-12 GO_WOUND_HEALING 1.146538e-11 GO_COLLAGEN_TRIMER 1.310481e-11 $`4` GO_CGMP_BIOSYNTHETIC_PROCESS 0.0002763958 GO_REGULATION_OF_SERINE_TYPE_PEPTIDASE_ACTIVITY 0.0002763958 GO_REGULATION_OF_NOREPINEPHRINE_SECRETION 0.0002763958 GO_THYROID_HORMONE_METABOLIC_PROCESS 0.0002763958 GO_NEGATIVE_REGULATION_OF_SERINE_TYPE_PEPTIDASE_ACTIVITY 0.0002763958 GO_SPINAL_CORD_ASSOCIATION_NEURON_DIFFERENTIATION 0.0002763958 GO_URATE_METABOLIC_PROCESS 0.0002763958 GO_REGULATION_OF_TRANSMISSION_OF_NERVE_IMPULSE 0.0002763958 GO_CELLULAR_GLUCURONIDATION 0.0002763958 GO_DOPAMINE_TRANSPORT 0.0002763958 $`5` GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION 0 GO_CARDIAC_CHAMBER_DEVELOPMENT 0 GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY 0 GO_CIRCADIAN_RHYTHM 0 GO_PHOSPHATIDYLSERINE_ACYL_CHAIN_REMODELING 0 GO_SPINAL_CORD_DEVELOPMENT 0 GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY 0 GO_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS 0 GO_REGULATION_OF_NLRP3_INFLAMMASOME_COMPLEX_ASSEMBLY 0 GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION 0 # A tibble: 2 x 7 # Groups: cluster [2] p_val avg_logFC pct.1 pct.2 p_val_adj cluster gene 1 3.15e-16 0.518 0.586 0.226 3.42e-12 m_SPARC SPARC 2 8.33e-10 0.442 0.581 0.289 9.04e- 6 m_COL1A1 COL1A1 $m_MGP GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION 0 GO_CARDIAC_CHAMBER_DEVELOPMENT 0 GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY 0 GO_CIRCADIAN_RHYTHM 0 GO_PHOSPHATIDYLSERINE_ACYL_CHAIN_REMODELING 0 GO_SPINAL_CORD_DEVELOPMENT 0 GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY 0 GO_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS 0 GO_REGULATION_OF_NLRP3_INFLAMMASOME_COMPLEX_ASSEMBLY 0 GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION 0 $m_GPX4 GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION 0 GO_CARDIAC_CHAMBER_DEVELOPMENT 0 GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY 0 GO_CIRCADIAN_RHYTHM 0 GO_PHOSPHATIDYLSERINE_ACYL_CHAIN_REMODELING 0 GO_SPINAL_CORD_DEVELOPMENT 0 GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY 0 GO_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS 0 GO_REGULATION_OF_NLRP3_INFLAMMASOME_COMPLEX_ASSEMBLY 0 GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION 0 $m_SCGB1D2 GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION 0 GO_CARDIAC_CHAMBER_DEVELOPMENT 0 GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY 0 GO_CIRCADIAN_RHYTHM 0 GO_PHOSPHATIDYLSERINE_ACYL_CHAIN_REMODELING 0 GO_SPINAL_CORD_DEVELOPMENT 0 GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY 0 GO_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS 0 GO_REGULATION_OF_NLRP3_INFLAMMASOME_COMPLEX_ASSEMBLY 0 GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION 0 $m_OGT GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION 0 GO_CARDIAC_CHAMBER_DEVELOPMENT 0 GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY 0 GO_CIRCADIAN_RHYTHM 0 GO_PHOSPHATIDYLSERINE_ACYL_CHAIN_REMODELING 0 GO_SPINAL_CORD_DEVELOPMENT 0 GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY 0 GO_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS 0 GO_REGULATION_OF_NLRP3_INFLAMMASOME_COMPLEX_ASSEMBLY 0 GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION 0 $m_SPARC GO_PLATELET_ALPHA_GRANULE_LUMEN GO_SECRETORY_GRANULE_LUMEN 3.464434e-14 1.786623e-13 GO_PLATELET_ALPHA_GRANULE GO_VESICLE_LUMEN 5.579615e-13 9.814820e-13 GO_PLATELET_DEGRANULATION GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION 5.592484e-12 3.396910e-11 GO_EXTRACELLULAR_MATRIX GO_REGULATED_EXOCYTOSIS 4.289123e-11 3.791488e-10 GO_BASEMENT_MEMBRANE GO_PROTEINACEOUS_EXTRACELLULAR_MATRIX 9.852178e-10 1.214490e-09 $m_COL1A1 GO_SKELETAL_SYSTEM_DEVELOPMENT 0.000000e+00 GO_EXTRACELLULAR_MATRIX 0.000000e+00 GO_EXTRACELLULAR_SPACE 0.000000e+00 GO_PROTEIN_HETEROTRIMERIZATION 2.251816e-09 GO_PLATELET_DERIVED_GROWTH_FACTOR_BINDING 2.251816e-09 GO_BANDED_COLLAGEN_FIBRIL 3.096033e-09 GO_CELLULAR_RESPONSE_TO_VITAMIN 5.365715e-09 GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA 6.513060e-09 GO_COMPLEX_OF_COLLAGEN_TRIMERS 1.817210e-08 GO_CELLULAR_RESPONSE_TO_NUTRIENT 2.887433e-08 $m_MGP [1] "MGP" "COX6C" "GNB1" "TFF1" "PCSK6" "NTPCR" "SH3BGR" $m_GPX4 [1] "GPX4" "ABCF2.1" "LLGL2" "SRA1" "CRABP2" "IFI6" "ISG15" [8] "ZFPL1" "NME1" "TFF3" "S100A10" "MAGED2" "PRR14" "AP2S1" [15] "ARAP1" "SRSF10" "SPP1" $m_SCGB1D2 [1] "SCGB1D2" "RBM47" "CSAD" "RBBP4" "SKP1" $m_OGT [1] "OGT" "EEF1A1" "VKORC1" "SSBP1" "ARL6IP4" "PLEC" [7] "IGFBP4" "COPE" "NPDC1" "HSPG2" "HLA-DQB1" "TNFRSF14" [13] "LONP2" "FZR1" "APOE" "IGFBP2" "CMC1" "TKT" [19] "ACTN1" "EMP1" "DPM2" $m_SPARC [1] "SPARC" "FN1" "TMSB4X" "IGFBP7" "VWF" "COL4A1" "VIM" [8] "MYL9" "HLA-E" "A2M" "EGFL7" "COL4A2" "IGFBP3" "SAT1" [15] "PDGFRB" "COL18A1" "HLA-A" $m_COL1A1 [1] "COL1A1" "MMP11" "COL1A2" "AEBP1" "POSTN" "LUM" [7] "COL3A1" "LINC01641" "LUC7L" "FTL" "DCN" "ENO1" [13] "GGA1" "THY1" "C3" "UBC" "THBS2" "CSNK2B" [19] "VBP1" m_MGP [1,] "GO_RHODOPSIN_MEDIATED_SIGNALING_PATHWAY" [2,] "GO_PHOTORECEPTOR_DISC_MEMBRANE" [3,] "GO_PHOTOTRANSDUCTION_VISIBLE_LIGHT" [4,] "GO_ADENYLATE_CYCLASE_ACTIVATING_DOPAMINE_RECEPTOR_SIGNALING_PATHWAY" [5,] "GO_PHOTORECEPTOR_OUTER_SEGMENT_MEMBRANE" [6,] "GO_TRIPARTITE_REGIONAL_SUBDIVISION" [7,] "GO_RESPONSE_TO_ACETYLCHOLINE" [8,] "GO_MAINTENANCE_OF_GASTROINTESTINAL_EPITHELIUM" [9,] "GO_BLASTODERM_SEGMENTATION" [10,] "GO_ANGIOTENSIN_RECEPTOR_BINDING" m_GPX4 [1,] "GO_REGULATION_OF_COLLATERAL_SPROUTING" [2,] "GO_LIPOXYGENASE_PATHWAY" [3,] "GO_RETINOIC_ACID_METABOLIC_PROCESS" [4,] "GO_RETINAL_BINDING" [5,] "GO_RETINOL_BINDING" [6,] "GO_RETINOIC_ACID_BINDING" [7,] "GO_POSITIVE_REGULATION_OF_BONE_REMODELING" [8,] "GO_INTERMEDIATE_FILAMENT_BINDING" [9,] "GO_CLATHRIN_COAT_ASSEMBLY" [10,] "GO_ANGIOTENSIN_RECEPTOR_BINDING" m_SCGB1D2 [1,] "GO_PCG_PROTEIN_COMPLEX" [2,] "GO_CULLIN_FAMILY_PROTEIN_BINDING" [3,] "GO_SIN3_COMPLEX" [4,] "GO_HISTONE_H2A_MONOUBIQUITINATION" [5,] "GO_SIN3_TYPE_COMPLEX" [6,] "GO_CHD_TYPE_COMPLEX" [7,] "GO_ESC_E_Z_COMPLEX" [8,] "GO_HISTONE_H2A_UBIQUITINATION" [9,] "GO_DNA_REPLICATION_DEPENDENT_NUCLEOSOME_ORGANIZATION" [10,] "GO_NUCLEAR_TRANSCRIPTIONAL_REPRESSOR_COMPLEX" m_OGT [1,] "GO_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY" [2,] "GO_ISOPRENOID_METABOLIC_PROCESS" [3,] "GO_INSULIN_LIKE_GROWTH_FACTOR_BINDING" [4,] "GO_REGULATION_OF_CYTOKINE_SECRETION_INVOLVED_IN_IMMUNE_RESPONSE" [5,] "GO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_REMODELING" [6,] "GO_REGULATION_OF_CGMP_BIOSYNTHETIC_PROCESS" [7,] "GO_CHOLESTEROL_TRANSPORTER_ACTIVITY" [8,] "GO_SYNAPTIC_TRANSMISSION_CHOLINERGIC" [9,] "GO_PROTEIN_CARBOXYLATION" [10,] "GO_LIPOPROTEIN_METABOLIC_PROCESS" m_SPARC [1,] "GO_PLATELET_ALPHA_GRANULE_LUMEN" [2,] "GO_EXTRACELLULAR_MATRIX" [3,] "GO_SECRETORY_GRANULE_LUMEN" [4,] "GO_PLATELET_ALPHA_GRANULE" [5,] "GO_VESICLE_LUMEN" [6,] "GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION" [7,] "GO_ANGIOGENESIS" [8,] "GO_BASEMENT_MEMBRANE" [9,] "GO_PLATELET_DEGRANULATION" [10,] "GO_BLOOD_VESSEL_MORPHOGENESIS" m_COL1A1 [1,] "GO_EXTRACELLULAR_MATRIX" [2,] "GO_COMPLEX_OF_COLLAGEN_TRIMERS" [3,] "GO_PROTEINACEOUS_EXTRACELLULAR_MATRIX" [4,] "GO_COLLAGEN_FIBRIL_ORGANIZATION" [5,] "GO_BANDED_COLLAGEN_FIBRIL" [6,] "GO_EXTRACELLULAR_MATRIX_COMPONENT" [7,] "GO_COLLAGEN_TRIMER" [8,] "GO_EXTRACELLULAR_SPACE" [9,] "GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION" [10,] "GO_PLATELET_DERIVED_GROWTH_FACTOR_BINDING"